Many have hailed the widespread use of generic drugs as one of the most important public-health developments of the twenty-first century. Today, almost 90 percent of our pharmaceutical market is comprised of generics, the majority of which are manufactured overseas. We have been reassured by our doctors, our pharmacists and our regulators that generic drugs are identical to their brand-name counterparts, just less expensive. But is this really true?
Katherine Eban’s Bottle of Lies exposes the deceit behind generic-drug manufacturing—and the attendant risks for global health. Drawing on exclusive accounts from whistleblowers and regulators, as well as thousands of pages of confidential FDA documents, Eban reveals an industry where fraud is rampant, companies routinely falsify data, and executives circumvent almost every principle of safe manufacturing to minimize cost and maximize profit, confident in their ability to fool inspectors. Meanwhile, patients unwittingly consume medicine with unpredictable and dangerous effects.
The story of generic drugs is truly global. It connects middle America to China, India, sub-Saharan Africa and Brazil, and represents the ultimate litmus test of globalization: what are the risks of moving drug manufacturing offshore, and are they worth the savings?
A decade-long investigation with international sweep, high-stakes brinkmanship and big money at its core, Bottle of Lies reveals how the world’s greatest public-health innovation has become one of its most astonishing swindles.
##醫藥版本的長夜難明。
評分##做瞭心理建設還是很難相信這種骯髒勾當是廣泛存在的,FDA的形式主義和無所作為也是視人命如草芥
評分##闊怕 保命請認準大廠原研藥 以及第三世界真實從頭慘到腳
評分##Generic drugs still have a long way to go
評分##讀瞭三分之二終究還是決定放棄瞭????一個理科生隻想看是啥原理導緻仿製藥的巨大問題,卻不太想知道中間那麼多復雜而又牽扯巨多的故事細節????????????然鵝這本書連uplcms都要解釋一下但沒解釋清楚。。。
評分觸目驚心,我國石傢莊一傢藥企“上榜”,生産的無效頭孢在非洲緻兒童死亡,中文版裏不知能否保留
評分##這本書給我感覺和bad blood很像,也是一個記者多方訪談追蹤揭露製藥廠的騙局,讀下來觸目驚心,一遍遍問這是真的嗎?真的嗎?怎麼會這樣?FDA完全不可信瞭?簡單結論就是韆萬不要再吃generic drugs瞭!
評分##investigative journalism比偵探懸疑武俠都好讀!本來是要堅定信心好好賺錢just so that I can pay whatever for the non generics,後麵讀到drug resistance那段覺得也無所謂瞭,????大傢一起玩完。
評分##簡直是觸目驚心的一本書,4.5星,半星給寫作的重復性打摺掉。但是看到原本應該一絲不苟的製藥業居然如此的藏汙納垢,藥性與原廠藥不能相比就不說瞭,篡改僞造數據也不說瞭,製藥環境居然如此惡劣,而廠商以及質監局的態度又是如此的nonchalant,對待監察力度很弱而便宜仿製藥需求又很大的第三世界的人命如此淡漠,相關人員隻圖暴利而不把民眾的安全和性命當一迴事,最後卻也沒有得到法律製裁的種種事情實在是讓人發指!立馬把傢長吃的藥趕快拿來查一下是不是也有質量不過關的問題。。。
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