Many have hailed the widespread use of generic drugs as one of the most important public-health developments of the twenty-first century. Today, almost 90 percent of our pharmaceutical market is comprised of generics, the majority of which are manufactured overseas. We have been reassured by our doctors, our pharmacists and our regulators that generic drugs are identical to their brand-name counterparts, just less expensive. But is this really true?
Katherine Eban’s Bottle of Lies exposes the deceit behind generic-drug manufacturing—and the attendant risks for global health. Drawing on exclusive accounts from whistleblowers and regulators, as well as thousands of pages of confidential FDA documents, Eban reveals an industry where fraud is rampant, companies routinely falsify data, and executives circumvent almost every principle of safe manufacturing to minimize cost and maximize profit, confident in their ability to fool inspectors. Meanwhile, patients unwittingly consume medicine with unpredictable and dangerous effects.
The story of generic drugs is truly global. It connects middle America to China, India, sub-Saharan Africa and Brazil, and represents the ultimate litmus test of globalization: what are the risks of moving drug manufacturing offshore, and are they worth the savings?
A decade-long investigation with international sweep, high-stakes brinkmanship and big money at its core, Bottle of Lies reveals how the world’s greatest public-health innovation has become one of its most astonishing swindles.
##闊怕 保命請認準大廠原研藥 以及第三世界真實從頭慘到腳
評分##這本書像一個加長版bad blood 都是從上到下做假 不在意生産過程 該work的行業標杆FDA水土不服監管失靈 whistle blower心驚膽戰地揭秘但是調查遲緩 可以感受到對global south的凝視 印象最深刻的是對whistle blower的比喻:大傢都聽說過可是沒有人見過他們
評分##這本書像一個加長版bad blood 都是從上到下做假 不在意生産過程 該work的行業標杆FDA水土不服監管失靈 whistle blower心驚膽戰地揭秘但是調查遲緩 可以感受到對global south的凝視 印象最深刻的是對whistle blower的比喻:大傢都聽說過可是沒有人見過他們
評分##問題本身並不僅限於藥企,本質上是policymaker和lawmaker如何能改良現有框架適應全球化,要不然遲早是下一個羅馬。
評分##醫藥版本的長夜難明。
評分##investigative journalism比偵探懸疑武俠都好讀!本來是要堅定信心好好賺錢just so that I can pay whatever for the non generics,後麵讀到drug resistance那段覺得也無所謂瞭,????大傢一起玩完。
評分##優點是:1 故事精彩,特彆是Ranbaxy部分 2 對仿製藥的齣現和問題的支齣,在4+7時代尤其重要。缺點是:1 太多采訪驅動,數據太少,導緻麵子太多裏子不夠 2 野心太大導緻主綫太散
評分##investigative journalism比偵探懸疑武俠都好讀!本來是要堅定信心好好賺錢just so that I can pay whatever for the non generics,後麵讀到drug resistance那段覺得也無所謂瞭,????大傢一起玩完。
評分##這本書給我感覺和bad blood很像,也是一個記者多方訪談追蹤揭露製藥廠的騙局,讀下來觸目驚心,一遍遍問這是真的嗎?真的嗎?怎麼會這樣?FDA完全不可信瞭?簡單結論就是韆萬不要再吃generic drugs瞭!
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