具体描述
Many have hailed the widespread use of generic drugs as one of the most important public-health developments of the twenty-first century. Today, almost 90 percent of our pharmaceutical market is comprised of generics, the majority of which are manufactured overseas. We have been reassured by our doctors, our pharmacists and our regulators that generic drugs are identical to their brand-name counterparts, just less expensive. But is this really true?
Katherine Eban’s Bottle of Lies exposes the deceit behind generic-drug manufacturing—and the attendant risks for global health. Drawing on exclusive accounts from whistleblowers and regulators, as well as thousands of pages of confidential FDA documents, Eban reveals an industry where fraud is rampant, companies routinely falsify data, and executives circumvent almost every principle of safe manufacturing to minimize cost and maximize profit, confident in their ability to fool inspectors. Meanwhile, patients unwittingly consume medicine with unpredictable and dangerous effects.
The story of generic drugs is truly global. It connects middle America to China, India, sub-Saharan Africa and Brazil, and represents the ultimate litmus test of globalization: what are the risks of moving drug manufacturing offshore, and are they worth the savings?
A decade-long investigation with international sweep, high-stakes brinkmanship and big money at its core, Bottle of Lies reveals how the world’s greatest public-health innovation has become one of its most astonishing swindles.
用户评价
##触目惊心，肺炎疫情期间看更有额外的感慨。关于天朝那一段估计中文版会删吧……
评分##看到在FDA调查员住的酒店装监听器真的看得我毛骨悚然，后面真的心疼baker和thakur。一个辛辛苦苦找fraudelence的证据后给出OAI，agency却为了指标downgrade to VAI，lift ban...一个为了正义做whistleblower，说因此导致妻离子散，家破人亡也不为过。 难道只要有药，就可以不论质量地给病人吃吗。 如果代表着最高标准的FDA都是这样让人心寒，我们还能相信谁。难道以后大家保命只能花巨额买brand-name吗.. 对lal，baker，thakur等战士表示敬意，对Katherine Eban在内的所有调查记者致以敬意。因为他们，我们才离真相越来越近。也因此看清了善与恶的对抗不过是以卵击石。一切正义行为在利益面前都是如此不堪一击。
评分##阔怕 保命请认准大厂原研药 以及第三世界真实从头惨到脚
评分##简直是触目惊心的一本书，4.5星，半星给写作的重复性打折掉。但是看到原本应该一丝不苟的制药业居然如此的藏污纳垢，药性与原厂药不能相比就不说了，篡改伪造数据也不说了，制药环境居然如此恶劣，而厂商以及质监局的态度又是如此的nonchalant，对待监察力度很弱而便宜仿制药需求又很大的第三世界的人命如此淡漠，相关人员只图暴利而不把民众的安全和性命当一回事，最后却也没有得到法律制裁的种种事情实在是让人发指！立马把家长吃的药赶快拿来查一下是不是也有质量不过关的问题。。。
评分##读了三分之二终究还是决定放弃了????一个理科生只想看是啥原理导致仿制药的巨大问题，却不太想知道中间那么多复杂而又牵扯巨多的故事细节????????????然鹅这本书连uplcms都要解释一下但没解释清楚。。。
评分##an astonishing scandal involving people desperate for cheap drugs, "meaningless" efforts made by individuals, "evil" companies, historically do-nothing FDA, politics and poor regulations. yet sadly the same story will happen again and again and again.
评分##阔怕 保命请认准大厂原研药 以及第三世界真实从头惨到脚
评分##优点是：1 故事精彩，特别是Ranbaxy部分 2 对仿制药的出现和问题的支出，在4+7时代尤其重要。缺点是：1 太多采访驱动，数据太少，导致面子太多里子不够 2 野心太大导致主线太散
评分##阔怕 保命请认准大厂原研药 以及第三世界真实从头惨到脚
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