Many have hailed the widespread use of generic drugs as one of the most important public-health developments of the twenty-first century. Today, almost 90 percent of our pharmaceutical market is comprised of generics, the majority of which are manufactured overseas. We have been reassured by our doctors, our pharmacists and our regulators that generic drugs are identical to their brand-name counterparts, just less expensive. But is this really true?
Katherine Eban’s Bottle of Lies exposes the deceit behind generic-drug manufacturing—and the attendant risks for global health. Drawing on exclusive accounts from whistleblowers and regulators, as well as thousands of pages of confidential FDA documents, Eban reveals an industry where fraud is rampant, companies routinely falsify data, and executives circumvent almost every principle of safe manufacturing to minimize cost and maximize profit, confident in their ability to fool inspectors. Meanwhile, patients unwittingly consume medicine with unpredictable and dangerous effects.
The story of generic drugs is truly global. It connects middle America to China, India, sub-Saharan Africa and Brazil, and represents the ultimate litmus test of globalization: what are the risks of moving drug manufacturing offshore, and are they worth the savings?
A decade-long investigation with international sweep, high-stakes brinkmanship and big money at its core, Bottle of Lies reveals how the world’s greatest public-health innovation has become one of its most astonishing swindles.
##Generic drugs still have a long way to go
评分触目惊心,我国石家庄一家药企“上榜”,生产的无效头孢在非洲致儿童死亡,中文版里不知能否保留
评分##医药版本的长夜难明。
评分##读了三分之二终究还是决定放弃了????一个理科生只想看是啥原理导致仿制药的巨大问题,却不太想知道中间那么多复杂而又牵扯巨多的故事细节????????????然鹅这本书连uplcms都要解释一下但没解释清楚。。。
评分##简直是触目惊心的一本书,4.5星,半星给写作的重复性打折掉。但是看到原本应该一丝不苟的制药业居然如此的藏污纳垢,药性与原厂药不能相比就不说了,篡改伪造数据也不说了,制药环境居然如此恶劣,而厂商以及质监局的态度又是如此的nonchalant,对待监察力度很弱而便宜仿制药需求又很大的第三世界的人命如此淡漠,相关人员只图暴利而不把民众的安全和性命当一回事,最后却也没有得到法律制裁的种种事情实在是让人发指!立马把家长吃的药赶快拿来查一下是不是也有质量不过关的问题。。。
评分##简直是触目惊心的一本书,4.5星,半星给写作的重复性打折掉。但是看到原本应该一丝不苟的制药业居然如此的藏污纳垢,药性与原厂药不能相比就不说了,篡改伪造数据也不说了,制药环境居然如此恶劣,而厂商以及质监局的态度又是如此的nonchalant,对待监察力度很弱而便宜仿制药需求又很大的第三世界的人命如此淡漠,相关人员只图暴利而不把民众的安全和性命当一回事,最后却也没有得到法律制裁的种种事情实在是让人发指!立马把家长吃的药赶快拿来查一下是不是也有质量不过关的问题。。。
评分##investigative journalism比侦探悬疑武侠都好读!本来是要坚定信心好好赚钱just so that I can pay whatever for the non generics,后面读到drug resistance那段觉得也无所谓了,????大家一起玩完。
评分##读了三分之二终究还是决定放弃了????一个理科生只想看是啥原理导致仿制药的巨大问题,却不太想知道中间那么多复杂而又牵扯巨多的故事细节????????????然鹅这本书连uplcms都要解释一下但没解释清楚。。。
评分##这本书像一个加长版bad blood 都是从上到下做假 不在意生产过程 该work的行业标杆FDA水土不服监管失灵 whistle blower心惊胆战地揭秘但是调查迟缓 可以感受到对global south的凝视 印象最深刻的是对whistle blower的比喻:大家都听说过可是没有人见过他们
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