具体描述
Many have hailed the widespread use of generic drugs as one of the most important public-health developments of the twenty-first century. Today, almost 90 percent of our pharmaceutical market is comprised of generics, the majority of which are manufactured overseas. We have been reassured by our doctors, our pharmacists and our regulators that generic drugs are identical to their brand-name counterparts, just less expensive. But is this really true?
Katherine Eban’s Bottle of Lies exposes the deceit behind generic-drug manufacturing—and the attendant risks for global health. Drawing on exclusive accounts from whistleblowers and regulators, as well as thousands of pages of confidential FDA documents, Eban reveals an industry where fraud is rampant, companies routinely falsify data, and executives circumvent almost every principle of safe manufacturing to minimize cost and maximize profit, confident in their ability to fool inspectors. Meanwhile, patients unwittingly consume medicine with unpredictable and dangerous effects.
The story of generic drugs is truly global. It connects middle America to China, India, sub-Saharan Africa and Brazil, and represents the ultimate litmus test of globalization: what are the risks of moving drug manufacturing offshore, and are they worth the savings?
A decade-long investigation with international sweep, high-stakes brinkmanship and big money at its core, Bottle of Lies reveals how the world’s greatest public-health innovation has become one of its most astonishing swindles.
用户评价
##an astonishing scandal involving people desperate for cheap drugs, "meaningless" efforts made by individuals, "evil" companies, historically do-nothing FDA, politics and poor regulations. yet sadly the same story will happen again and again and again.
评分##简直是触目惊心的一本书，4.5星，半星给写作的重复性打折掉。但是看到原本应该一丝不苟的制药业居然如此的藏污纳垢，药性与原厂药不能相比就不说了，篡改伪造数据也不说了，制药环境居然如此恶劣，而厂商以及质监局的态度又是如此的nonchalant，对待监察力度很弱而便宜仿制药需求又很大的第三世界的人命如此淡漠，相关人员只图暴利而不把民众的安全和性命当一回事，最后却也没有得到法律制裁的种种事情实在是让人发指！立马把家长吃的药赶快拿来查一下是不是也有质量不过关的问题。。。
评分##优点是：1 故事精彩，特别是Ranbaxy部分 2 对仿制药的出现和问题的支出，在4+7时代尤其重要。缺点是：1 太多采访驱动，数据太少，导致面子太多里子不够 2 野心太大导致主线太散
评分##问题本身并不仅限于药企，本质上是policymaker和lawmaker如何能改良现有框架适应全球化，要不然迟早是下一个罗马。
评分##首先，非常感谢作者在经过大量的访谈和研究之后写出这么一本精彩的书，很不易。其次，作者选择的话题让我震惊。真的是用震惊来形容都不过！都感觉不象是非虚构作品，而是一本惊悚小说。印度制药界是没有良心可言的，他们认为撒谎，作假是正常的，因为整个社会都是这样，有什么好奇怪的。就算是铁证如山，他们仍旧可以平静地看着你的眼睛，说，没有啊？这药好好的呀。FDA实在是机构臃肿，办事非常不利索。如果没有最出的whistler blower和自己的好员工，那么这个药厂的丑闻还不知道什么时候才能被揭露，而又会又多少病人因为药的不合格而死去。最后，这本书写得非常棒，文字功底厚，结构条例清晰。强烈推荐给任何对健康重视的人士。
评分##医药版本的长夜难明。
评分##看到在FDA调查员住的酒店装监听器真的看得我毛骨悚然，后面真的心疼baker和thakur。一个辛辛苦苦找fraudelence的证据后给出OAI，agency却为了指标downgrade to VAI，lift ban...一个为了正义做whistleblower，说因此导致妻离子散，家破人亡也不为过。 难道只要有药，就可以不论质量地给病人吃吗。 如果代表着最高标准的FDA都是这样让人心寒，我们还能相信谁。难道以后大家保命只能花巨额买brand-name吗.. 对lal，baker，thakur等战士表示敬意，对Katherine Eban在内的所有调查记者致以敬意。因为他们，我们才离真相越来越近。也因此看清了善与恶的对抗不过是以卵击石。一切正义行为在利益面前都是如此不堪一击。
评分##investigative journalism比侦探悬疑武侠都好读！本来是要坚定信心好好赚钱just so that I can pay whatever for the non generics，后面读到drug resistance那段觉得也无所谓了，????大家一起玩完。
评分##bad blood, billion dollar whale... fraud seems everywhere and beyond my wild imagination... one whistle blower against the world.. how many of us are brave enough to do this? luckily sometimes one would be sufficient
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