發表於2025-05-25
Bottle of Lies: The Inside Story of the Generic Drug Boom pdf epub mobi txt 電子書 下載
Katherine Eban, an investigative journalist, is a Fortune magazine contributor and Andrew Carnegie fellow. Her narrative, deeply reported articles on pharmaceutical counterfeiting, gun trafficking, and coercive interrogations by the CIA, have won international attention and numerous awards. She lectures frequently on the topic of pharmaceutical integrity. Bottle of Lies: The Inside Story of the Generic Drug Boom, which she worked on for five years and reported on four continents, is her second book. Educated at Brown University and Oxford, where she was a Rhodes Scholar, she lives in Brooklyn with her husband, two daughters and Newfoundland dog Romeo.
Many have hailed the widespread use of generic drugs as one of the most important public-health developments of the twenty-first century. Today, almost 90 percent of our pharmaceutical market is comprised of generics, the majority of which are manufactured overseas. We have been reassured by our doctors, our pharmacists and our regulators that generic drugs are identical to their brand-name counterparts, just less expensive. But is this really true?
Katherine Eban’s Bottle of Lies exposes the deceit behind generic-drug manufacturing—and the attendant risks for global health. Drawing on exclusive accounts from whistleblowers and regulators, as well as thousands of pages of confidential FDA documents, Eban reveals an industry where fraud is rampant, companies routinely falsify data, and executives circumvent almost every principle of safe manufacturing to minimize cost and maximize profit, confident in their ability to fool inspectors. Meanwhile, patients unwittingly consume medicine with unpredictable and dangerous effects.
The story of generic drugs is truly global. It connects middle America to China, India, sub-Saharan Africa and Brazil, and represents the ultimate litmus test of globalization: what are the risks of moving drug manufacturing offshore, and are they worth the savings?
A decade-long investigation with international sweep, high-stakes brinkmanship and big money at its core, Bottle of Lies reveals how the world’s greatest public-health innovation has become one of its most astonishing swindles.
##也許大部分並不知道,仿製藥如今在任何國傢,其實都是藥品的“主流”,我們能夠買到的絕大多數藥品,都是各種各樣的仿製藥。與仿製藥對應的,就是作者在這本書中為之張目的原研藥。然而有能力生産原研藥的,也隻有全球幾大製藥巨頭,因為需要投入大量的科研經費、人力物力,而...
評分##仿製藥“應該”是同等療效、價格低廉的替代品,但誠如書中所說的嚴重違規、為瞭利益藐視生命的行為一定存在。而這些行為不是仿製藥獨有的,品牌藥藥企同樣也有不公布所有臨床試驗數據、不提交嚴重不良反應事件等等違規害命的行為。最後受傷的總是患者。不管是仿製藥還是品牌藥...
評分##如短評所述,本書是令人震驚和恐懼的行業揭秘。對美國(也許和中國)而言,麵臨的是仿製藥的質量問題(甚至副作用)和價格惠民的矛盾。法律法規和管理辦法某種程度上激勵企業進行冒險和不道德行為,最終造成道德風險和逆嚮選擇。事實上,這一問題廣泛存在,無論是藥品,還是更...
評分##bad blood, billion dollar whale... fraud seems everywhere and beyond my wild imagination... one whistle blower against the world.. how many of us are brave enough to do this? luckily sometimes one would be sufficient
評分 評分 評分 評分 評分Bottle of Lies: The Inside Story of the Generic Drug Boom pdf epub mobi txt 電子書 下載