发表于2024-09-19
Bottle of Lies: The Inside Story of the Generic Drug Boom pdf epub mobi txt 电子书 下载
Katherine Eban, an investigative journalist, is a Fortune magazine contributor and Andrew Carnegie fellow. Her narrative, deeply reported articles on pharmaceutical counterfeiting, gun trafficking, and coercive interrogations by the CIA, have won international attention and numerous awards. She lectures frequently on the topic of pharmaceutical integrity. Bottle of Lies: The Inside Story of the Generic Drug Boom, which she worked on for five years and reported on four continents, is her second book. Educated at Brown University and Oxford, where she was a Rhodes Scholar, she lives in Brooklyn with her husband, two daughters and Newfoundland dog Romeo.
Many have hailed the widespread use of generic drugs as one of the most important public-health developments of the twenty-first century. Today, almost 90 percent of our pharmaceutical market is comprised of generics, the majority of which are manufactured overseas. We have been reassured by our doctors, our pharmacists and our regulators that generic drugs are identical to their brand-name counterparts, just less expensive. But is this really true?
Katherine Eban’s Bottle of Lies exposes the deceit behind generic-drug manufacturing—and the attendant risks for global health. Drawing on exclusive accounts from whistleblowers and regulators, as well as thousands of pages of confidential FDA documents, Eban reveals an industry where fraud is rampant, companies routinely falsify data, and executives circumvent almost every principle of safe manufacturing to minimize cost and maximize profit, confident in their ability to fool inspectors. Meanwhile, patients unwittingly consume medicine with unpredictable and dangerous effects.
The story of generic drugs is truly global. It connects middle America to China, India, sub-Saharan Africa and Brazil, and represents the ultimate litmus test of globalization: what are the risks of moving drug manufacturing offshore, and are they worth the savings?
A decade-long investigation with international sweep, high-stakes brinkmanship and big money at its core, Bottle of Lies reveals how the world’s greatest public-health innovation has become one of its most astonishing swindles.
##看到在FDA调查员住的酒店装监听器真的看得我毛骨悚然,后面真的心疼baker和thakur。一个辛辛苦苦找fraudelence的证据后给出OAI,agency却为了指标downgrade to VAI,lift ban...一个为了正义做whistleblower,说因此导致妻离子散,家破人亡也不为过。 难道只要有药,就可以不论质量地给病人吃吗。 如果代表着最高标准的FDA都是这样让人心寒,我们还能相信谁。难道以后大家保命只能花巨额买brand-name吗.. 对lal,baker,thakur等战士表示敬意,对Katherine Eban在内的所有调查记者致以敬意。因为他们,我们才离真相越来越近。也因此看清了善与恶的对抗不过是以卵击石。一切正义行为在利益面前都是如此不堪一击。
评分 评分 评分##读了三分之二终究还是决定放弃了?一个理科生只想看是啥原理导致仿制药的巨大问题,却不太想知道中间那么多复杂而又牵扯巨多的故事细节???然鹅这本书连uplcms都要解释一下但没解释清楚。。。
评分##在这本书之前,我对仿制药的了解可以用两句话讲完:理想很丰满,现实很骨感。 一方面,我理解为什么我们需要仿制药。广大穷人(包括我自己)都渴望推动仿制药的出现——因为救命的原研药实在太贵了,尤其是在美国医疗市场的环境中。 另一方面,我也明白为什么在医保改革之后,...
评分##问题本身并不仅限于药企,本质上是policymaker和lawmaker如何能改良现有框架适应全球化,要不然迟早是下一个罗马。
评分 评分##如果说bad blood带来的是震撼的话,bottle of lies带来的是死寂的绝望。推荐体验。 一个病人也救不了的仿制药,成了盛大的产业。人间辉煌。 再等待不超过三十年,产自印、中两国的仿制药会成为导致全球每年一千万人口死亡的重要因素之一。每年一千万。(COVID快两年了,总共死...
评分Bottle of Lies: The Inside Story of the Generic Drug Boom pdf epub mobi txt 电子书 下载